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Amino Acid Analysis Services Suppliers

Amino Acid Analysis (AAA) by RP-HPLC is used in protein characterization to analyse peptide or protein concentration, content and molar ratio or, alongside UV spectrophotometry, to gain an extinction coefficient. This analysis is used throughout all stages of drug discovery, or to demonstrate comparability and consistency between batches for release during the manufacturing phase. Amino acid analysis is a necessary part of protein characterisation and can also be used for estimation of extinction coefficient, total amino acids including cysteine, tryptophan, hydroxyproline & free amino acids, including asparagine & glutamine. By determination of extinction coefficient the method is validated for the product and includes molecular weight measurement by MALDI-TOF MS. The validated method may be used for batch release. Protein concentration may be calculated by relating extinction coefficient to Optical Density measurement, which is performed using a UV spectrometer at 280nm. Amino acid analysis is a key part of the ICH Q6B guidelines for characterisation and confirmation of biopharmaceuticals in support of new marketing applications.
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Velesco Pharmaceutical Services | Address: 46701 N. Commerce Center Dr. Suite A8, Plymouth, Michigan 48170, USA USA
www.velescopharma.com | Send Inquiry | Phone: +1-(734)-527-9124
Velesco Pharmaceutical Services is specialized in analytical method development, drug formulation, GMP manufacturing and pharmaceutical consulting. We are engaged in nimble, just-in-time cGMP drug pro more...
 
M-Scan, Inc. | Address: 606, Brandywine Parkway, West Chester, Pennsylvania 19380, USA USA
www.m-scan.com | Send Inquiry | Phone: +1-(610)-696-8210, 696-8240
M-Scan Inc. is a chemical analysis laboratory specializing in chemical testing as well as high-end GLP/GMP contract analytical services, consultancy & training based on mass spectrometry and chromatog more...
Bio-Synthesis, Inc. | Address: 612 East Main Street, Lewisville, Texas 75057, USA USA
www.biosyn.com | Send Inquiry | Phone: +1-(972)-420-8505, 800-227-0627
Bio-Synthesis, Inc. offers products for researchers and pharmaceutical companies. Our products include deoxyribonucleic acid (DNA), oligos, ribonucleic acid (RNA), locked nucleic acid (LNA), peptide n more...
Evans Analytical Group | Address: 810 Kifer Road, Sunnyvale, California 94086, USA USA
www.eaglabs.com | Send Inquiry | Phone: +001-(408)-530-3500
Evans Analytical Group offers services in surface analysis, trace elemental analysis, electron microscopy, failure analysis and circuit edit. We offer application solutions for adhesion & bonding, cle more...
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