Downstream Processing Suppliers

Downstream processing is primarily concerned with the initial separation of the bioreactor medium into a liquid phase & a solid phase and subsequent separation, concentration & purification of the product. Chemical engineering principles play a vital role here, as well in terms of designing and operation of the separation systems. Downstream processing costs can be as high as 60 - 70% of the selling price of the product as exemplified by the plant Eli Lilly built to produce human insulin. Over 90% of the 200 staff are involved in the recovery processes. Downstream processing represents a major part of the overall cost of most processes, but is also the least glamorous aspect of biotechnology. Improvements in downstream processing will benefit the overall efficiency and cost of processes and will make the biotechnology competitive to the conventional chemical processes. Downstream operations can play catch-up through conventional capacity-expanding strategies, for example by scaling up downstream equipment, employing multiple controllers for more rapid cleaning between steps, running fewer purification cycles (by scaling up column dimensions) or using media with higher throughput or binding capacity. Each solution has its benefits, as well as costs.
 EMAIL INQUIRY to  5 suppliers  
Molecular Depot LLC | Address: 7915 Silverton Ave #315, San Diego, California 92126, USA USA | Send Inquiry | Phone: +1-(858)-900-3210
Molecular Depot LLC specialize in the development of research tools and biochemicals. Our products include specialty bacterial culture media, antibodies & antigens, enzymes & proteins, chemical compou more...
Goodwin Biotechnology, Inc. | Address: 1850 N.W. 69th Avenue, Plantation, Florida 33313, USA USA | Send Inquiry | Phone: +1-(954)-321-5300
Goodwin Biotechnology, Inc. is a cGMP contract manufacturing organization (CMO) of monoclonal antibodies and recombinant proteins for preclinical & clinical trials. We offer services that include cell more...
DIREVO Industrial Biotechnology GmbH | Address: Nattermannallee 1, Cologne D - 50829, Germany Germany | Send Inquiry | Phone: +49-(221)-47448-0
DIREVO Industrial Biotechnolgy GmbH provides solutions through discovery, development & scale up of enzymes, other molecules & strains. Our portfolio includes optimized proteins, optimized bioprocesse more...
QSV Biologics Ltd. | Address: 1938 94 Street, Edmonton, Alberta T6N 1J3, Canada Canada | Send Inquiry | Phone: +1-(708)-438-5722
QSV Biologics Ltd. is a cGMP biologics contract manufacturer providing mammalian cell culture, microbial fermentation and purification services for the production of protein therapeutics, monoclonal a more...
Vogelbusch GmbH | Address: Blechturmgasse 11, Vienna 1051, Austria | Send Inquiry | Phone: +43-(1)-54661-0
Vogelbusch GmbH is an engineering company serving the biotech industry. We have two divisions such as biocommodities and biopharma. Our biocommodities produce products from raw materials in three step more...
 EMAIL INQUIRY to  5 Downstream Processing suppliers  
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