Phenotyping Services Suppliers
Specific phenotypic tests, such as body weight measurements, intraperitoneal injections, blood collection & urine testing can be performed subject to approval by the Animal Ethics and Experimentation Committee. The facility can also provide clinical chemistry analysis, flow cytometry and microarray analysis of tissues or sorted cells. Expert advice on developing or evaluating the results of specialized phenotyping tests is available through the network. Standard Phenotyping Services are, blood collection by retro-orbital bleed, tail vein, saphenous vein, jugular catheter and vena cava (attermination), blood samples are used for monitoring fasting & fed glucose levels in diabetic rats (T2DN,Zucker), isolation of either plasma or serum from blood for measurement of clinical chemistries or drug levels, ?24-hour urine collection for measurement of biomarkers for renal damage due to disease (nephropathy,ESRD) or drug toxicity, biomarkers include, but not limited to proteinuria & glucosuria, clinical chemistry analysis for measurement of biomarkers for kidney (BUN,creatinine), liver (ALT, AST, SDH) & heart (CK) damage, histopathology that includes organ preservation, generation of tissue slices, staining and scoring by certified pathologists. EUMORPHIA is an integrated research programme involving development of new approaches in phenotyping, mutagenesis & informatics leading to improved characterisation of mouse models for the understanding of human physiology and disease.
4100 Regent Street Suite M-2, Columbus, Ohio 43219, USA www.phylogenyinc.com
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Phylogeny, Inc. offers in situ hybridization, tissue procurement, microRNA in situ detection and phylogeny cytogenetics services. We deliver interpreted gene expression results from embryo to adult; f more...