Profile: Soluble Therapeutics, LLC specializes in offering solutions to stabilize proteins. HSC™ Technology, can rapidly determine the formula that provides stable and soluble proteins for use as therapeutics, vaccines, diagnostics & research reagents. Specifically HSC™ Technology can effectively measure the physical stability of membrane proteins & mutants, water soluble proteins, peptides, and complex mixtures. HSC™ Technology is an improvement over traditional methods due to the low sample consumption and high-throughput amenability, while providing useful information for both crystallization & formulation optimization. The Initial Screen is a three step method, using the patented HSC™ Technology, that begins the process of quantifying the effect that various solution additives have on the interaction of the protein in questions. The Discovery Screen is a multi-step process, using the patented HSC™ Technology, performed upon the completion of the Initial Screen. During the Discovery Screen we analyze numerous variations of the nine most promising additives in solution with respect to concentration and composition. As part of the Discovery Screen, a calorimetric analysis of the protein in the various solutions is performed to ensure that the protein has not lost its structure while in solution.
12 Products/Services (Click for related suppliers)
|•||Biomolecular Analysis||•||Custom Protein Expression Services||•||High Throughput Screening|
|•||Medicinal and Combinatorial Chemistry||•||Protein Crystallization||•||Protein Expression|
|•||Protein Expression Screening Services||•||Protein Optimization||•||Protein Purification|
|•||Protein Purification Services||•||X-ray Diffraction||•||X-Ray Diffraction Analysis|