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Profile: Takara Bio USA, Inc. provides kits, reagents, and services that help researchers engaged in gene discovery. We supply tools for studying gene expression, sub-cellular localization, apoptosis, and signal transduction. Our products include antibody arrays, fluorescent proteins & chemiluminescent reporter systems, mammalian expression systems, reverse transcription, RNA, nucleic acid purification, oligo modification, gene expression profiling, and cell signaling. Our protein extraction & labeling kit is a non-denaturing method for extracting mammalian proteins. This extract includes cytosolic and membrane proteins representing all major sub-cellular compartments. The non-denaturing protocol maintains protein conformation and solubility. The extraction consists of three main steps, which include mechanically disrupting the cells, solubilizing the cells, and centrifuging the extract. We are an ISO 9001:2000 certified company.