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Epigallocatechin gallate possess the most potent antioxidant activity of the catechins. Epigallocatechin gallate may provide health effects by protecting our cells from oxidative damage from free radicals. A number of chronic disease have been associated with free radical damage, including cancer, arteriosclerosis, heart diseases and accelerated aging. Epigallocatechin gallate interferes with many enzyme systems: it inhibits fast-binding and reversible fatty acid synthase, increases tyrosine phosphorylation of the insulin receptor, activation of ornithine decarboxylase. Epigallocatechin gallate can protect the DNA in the human cells from ultraviolet and visible radiation-induced damage.Epigallocatechin gallate may be effective in promoting fat oxidation and lowering body weight.
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One of the main problems of writing Systems Biology Markup Language ( SBML) file by hand is the use of the Mathematical Markup Language (MathML) to describe all the mathematical portions of the model. MathML expressions are long, complex & therefore error-prone. To facilitate the editing of mathematical expressions, a small equation editor has been designed based on jex. The user can type the equation as free text, in a natural infix notation, that is subsequently transformed into valid MathML using the subset of MathML elements supported by SBML . The math editor also provides several drop-down menus to display the different elements that are already defined in the model & can be included in the equation (again using the name instead of the id to improve the readability of the equation). There is also the possibility to add new SBML elements compartments, species or parameters from within the math editor window. This avoids the necessity to go back to the main window if the declaration of an element has been forgotten.
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