Laboratory notebooks represent an important part of the research and development workflow. The role of the laboratory notebook is to record work that was done so that research can be repeated, or avoided if the outcome was not the desired outcome, and to allow subsequent research to move forward based on previous results. Traditionally, the laboratory notebook medium is paper and data entries are handwritten. This medium is portable, easy to use, well understood by users, and with a little care, a durable method of recording. The incorporation of high-throughput screening (HTS) and high-throughput synthesis into the research process has resulted in an increased volume of electronic data that needs to be transcribed resulting in the use of electronic notebooks. Electronic note books allow one to perform searches using combined criteria across text, metadata, chemical structures & reactions and thus mine your knowledge base in a very precise manner. Search results can be exported to create reports.